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How long does it take for Mirapex to kick in? Mirapex onsets in about 1-2 hours (depending on the individual's metabolism). Generally, it is taken only 1-2 hours before symptoms occur and it will last about 6-10 hours after each dose.
What causes internal restlessness? The main culprit in cases of akathisia is older antipsychotic drugs, though antidepressants are also implicated. The biggest cause of akathisia is high-strength, first-generation antipsychotic medications. The next biggest at-risk group for the condition is patients taking neuroleptic drugs.
Can you have restless leg syndrome while awake? People who have RLS and PLMS have trouble both falling asleep and staying asleep and may experience extreme sleepiness during the day. As a result of problems both in sleeping and while awake, people with RLS may have difficulties with their job, social life, and recreational activities.
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