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Can you stop digoxin abruptly? Do not stop taking digoxin without first talking to your doctor. Stopping suddenly may make your condition worse. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Digoxin overdose can occur more easily if you are dehydrated.
How does digoxin work in the body? Digoxin increases the force of contraction of the muscle of the heart by inhibiting the activity of an enzyme (ATPase) that controls movement of calcium, sodium, and potassium into heart muscle. During rapid atrial rhythms, electrical signals from the atria cause rapid contractions of the ventricles.
Is digoxin used anymore? Digoxin and HF Digoxin is effective in patients with CHF because of its positive inotropic properties. Although studies have shown that digoxin reduces hospitalizations and improves symptoms of HF, it has not been proven to decrease mortality. Digoxin's role in HF has been assessed in numerous trials.
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