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Does narcan reverse hydrocodone? What Is Naloxone And What Does It Treat? Naloxone is a medication designed to rapidly reverse opioid overdose. Naloxone is an opioid antagonist, meaning it binds to the opioid receptors to reverse /block the effects of other opioids such as heroin or certain pain medications (e.g., oxycodone, morphine, hydrocodone).
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